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Common borosilicate glass vials, even though remaining a long-standing staple in pharmaceutical packaging, can present sure restrictions which could pose some difficulties to drug manufacturers and Health care companies. Mary TanPharmExec Web-site features news, marketplace Investigation, the latest traits and thoughts on the most recent developmen

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This reactive epoxide intermediate might react with amino acid residues of a CYP enzyme to variety drug-CYP (drug-protein) adducts (Scheme 6, pathway C). The development on the drug-CYP adducts may or may not reveal a time-dependent inactivation from the catalytic exercise of this CYP enzyme, with regards to the covalent binding of your reactive in

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